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| REVIEW ARTICLE |
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| Year : 2012 |
Volume
: 16 | Issue : 3 | Page
: 400-405 |
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Chemical and physical basics of routine formaldehyde fixation
Rooban Thavarajah, Vidya Kazhiyur Mudimbaimannar, Joshua Elizabeth, Umadevi Krishnamohan Rao, Kannan Ranganathan
Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India
Correspondence Address:
Rooban Thavarajah
Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, Chennai
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0973-029X.102496
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Formaldehyde is the widely employed fixative that has been studied for decades. The chemistry of fixation has been studied widely since the early 20 th century. However, very few studies have been focused on the actual physics/chemistry aspect of process of this fixation. This article attempts to explain the chemistry of formaldehyde fixation and also to study the physical aspects involved in the fixation. The factors involved in the fixation process are discussed using well documented mathematical and physical formulae. The deeper understanding of these factors will enable pathologist to optimize the factors and use them in their favor. |
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