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REVIEW ARTICLE |
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Year : 2018 |
Volume
: 22 | Issue : 2 | Page
: 279 |
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A review of artifacts in histopathology
Syed Ahmed Taqi1, Syed Abdus Sami2, Lateef Begum Sami3, Syed Ahmed Zaki4
1 Department of Oral and Maxillofacial Sciences, Division of Oral Pathology, Najran University College of Dentistry, Najran, Saudi Arabia 2 Department of Forensic Medicine, MGM Medical College and Hospital, Aurangabad, Maharashtra, India 3 Department of Physiology, MGM Medical College and Hospital, Aurangabad, Maharashtra, India 4 Department of Pediatrics, Thumbay Hospital, Dubai, UAE
Correspondence Address:
Syed Ahmed Taqi Department of Oral and Maxillofacial Sciences, Division of Oral Pathology, Najran University College of Dentistry, Najran Saudi Arabia
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jomfp.JOMFP_125_15
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Histopathological examination is considered as gold standard procedure for arriving at a final diagnosis of various lesions of the human body. However, it is limited by a number of alterations of normal morphologic and cytological features that occur as a result of presence of artifacts. These artifacts may occur during surgical removal, fixation, tissue processing, embedding and microtomy and staining and mounting procedures. They can even lead to complete uselessness of the tissue. It is therefore essential to identify the commonly occurring artifacts during histopathological interpretations of tissue sections. This article reviews the common artifacts encountered during slide examination alongside the remedial measures which can be undertaken to differentiate between an artifact and tissue constituent.
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