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| SYSTEMATIC REVIEW ARTICLE |
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| Year : 2021 |
Volume
: 25 | Issue : 3 | Page
: 503-508 |
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Efficacy of herbal alternatives in maintaining oral health in cancer patients: A systematic review
Nadeem Jeddy1, Nirmal Famila Bettie2, R Saravanan3, LJ Sai Lakshmi1, T Radhika1
1 Department of Oral Pathology and Microbiology, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India
2 Department of Prosthodontics, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India
3 Department of Orthodontics, Crown and Bridge, Thai Moogambigai Dental College and Hospital, Dr. M. G. R. Educational and Research Institute University, Chennai, Tamil Nadu, India
Correspondence Address:
L J Sai Lakshmi
Department of Oral Pathology and Microbiology, Thaimoogambigai Dental College and Hospital, Golden George Nagar, Mogappair, Chennai - 600 107, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jomfp.jomfp_507_20
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Herbal rinses possess different medicinal properties. Numerous studies have reported the usefulness of various herbal oral rinses. Few studies claimed that herbal rinses are superior to synthetic mouth rinses for certain purposes, but there appears to be a lack of sound scientific evidence to prove the efficacy of herbal rinses in controlling oral plaque in cancer patients. This review analyses the various clinical studies on herbal rinses and aims to find the safety and efficacy of red ginseng mouth rinses over other available mouth rinses in carcinoma patients. A thorough electronic search was conducted in various databases and 10 articles were included in the review based on the inclusion and exclusion criteria. The data extracted were tabulated and analyzed. The risk of bias table was drawn. Meta-analysis was not performed due to the heterogeneity of the included studies. Of the 10 clinical trials included in the review, three studies appeared to have low risk of bias. The mean follow-up period was 14 days, ranging from 7 to 21 days. The sample size in each study was reported to be between 10 and 50, except one study with 240 samples. Seven studies have reported a significant difference between the herbal mouth rinse group and the chlorhexidine group. Of all the herbal rinses, mouth rinses with ginger extracts show more efficacy over other herbal rinses and red ginseng appears to be a more safer herbal rinse. Based on the available evidence, herbal mouth rinses are comparable to synthetic mouth rinses in their anti-bacterial properties. The red ginseng with anti-bacterial, anti-inflammatory and anti-cancerous properties may be an alternative mouth rinse in cancer patients. However, further clinical trials with more samples are required for better evidence.
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